Sildapo is a combination of two medicines: Sildenafil and Dapoxetine, which treats male erectile dysfunction and premature ejaculation. Sildenafil is a phosphodiesterase type 5 inhibitor that works by increasing blood flow to the penis during sexual stimulation and enables its erection following sexual stimulation. Dapoxetine is a selective serotonin reuptake inhibitor that increases the level of serotonin in nerves to increase the time taken to ejaculate and improve control over ejaculation.